JC Virus

The JC virus is a common human polyomavirus, usually acquired during childhood and often asymptomatic in healthy individuals. However, it poses a significant risk for immunocompromised patients, potentially causing Progressive Multifocal Leukoencephalopathy (PML), a severe and often fatal brain disease. Diagnostic tools like PCR assays are essential for detecting JC virus DNA in cerebrospinal fluid or plasma. Timely diagnosis allows for immediate therapeutic intervention, such as adjusting immunosuppressive treatments. Understanding the presence and activity of the JC virus is vital for patient management, especially among those with weakened immune systems.