HLA-A3101 RealFast™ PCR Kit for Carbamazepine Hypersensitivity Screening

Carbamazepine is a widely prescribed medication for conditions such as epilepsy, bipolar disorder, and nerve pain. However, for some patients, it can cause severe hypersensitivity reactions like Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reactions with eosinophilia and systemic symptoms (DRESS). These conditions are potentially life-threatening, especially in individuals carrying certain genetic markers. The HLA-A31:01 and HLA-B15:02 RealFast™ PCR kits from Viennalab offer a quick and reliable way to screen for these genetic variants, helping clinicians identify patients who are at higher risk before starting carbamazepine therapy.

The HLA-A31:01 allele is associated with a wider range of hypersensitivity reactions across various populations, including Europeans and Japanese. By using the RealFast™ assays to screen for these alleles, healthcare providers can significantly reduce the risk of severe adverse reactions, as recommended by the FDA and the Clinical Pharmacogenetic Implementation Consortium (CPIC).

This PCR kit provides fast and accurate results, making it easier to make informed decisions about whether to prescribe carbamazepine. Both assays are simple to use and highly reliable, ensuring that patients receive the safest possible treatment. With the HLA-A31:01 RealFast™ PCR kits, you can offer personalized care and minimize the risk of serious drug reactions in your patients.