Dengue fever is a common mosquito-borne viral infection caused by four different serotypes of dengue virus: DENV-1, DENV-2, DENV-3 and DENV-4. Accurate identification of the specific serotype is essential for effective clinical management, as re-infection with a different serotype can lead to serious complications, including severe haemorrhage, shock and organ damage due to antibody-dependent enhancement (ADE).

The Dengue Serotyping iCassette (PCR-Fluorescence) is an advanced diagnostic tool designed to qualitatively detect and differentiate between these four dengue virus serotypes in serum samples. Using real-time multiplexed fluorescent PCR technology, this iCassette provides healthcare professionals with the critical information needed to guide treatment decisions and monitor disease progression.

The iCassette uses a magnetic bead transfer structure and process technology, as well as a material distributed mixing device structure. It is compatible with the Galaxy: Nano, Lite and Pro. The test can be performed on demand with no minimum batch size requirement, which is advantageous for clinics and hospitals that require rapid results. The fully automated sample magnetic beads extraction to qPCR process provides results in one and a half hours with minimal hands-on time, increasing laboratory efficiency and reducing patient waiting times.

The iCassette Dengue Virus Serotyping Diagnostic Kit is suitable with human serum samples. It is stored at 2-8°C and includes internal process control to ensure the accuracy and reliability of each test performed.

The iCassette is designed for use in clinical settings, where its fully automated process minimizes the risk of cross-contamination and ensures consistent, reliable results. By enabling precise serotyping of dengue infections, this iCassette supports better patient outcomes and helps in the prevention of severe dengue fever, making it an essential tool in the fight against this global health challenge.