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Nucleosome ctDNA

Short description

At Goffin, we proudly offer exclusive access to nucleosomal ctDNA (n-ctDNA), a premier reference material known for its exceptionally low mutation background noise. This product enables highly sensitive Limits of Blank (LOB), Detection (LOD), and Quantification (LOQ) in Next Generation Sequencing (NGS) assays, including Minimal Residual Disease (MRD) testing.

Derived from SensID’s proprietary lymphoblastoid cell line (BDXXP4), our n-ctDNA features an impressively low error rate and high library conversion efficiency. Its patient-like fragmentation pattern makes it ideal for liquid biopsy research, diagnostics, and clinical trials. Additionally, Goffin can accommodate custom production from other cell lines upon request.

Product highlights

  • Optimized for Digital PCR and NGS
  • Supports Protocol Validation
  • Determines Detection Limits
  • Useful for various research and clinical settings

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Nucleosome ctDNA

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Specifications of the Nucleosome ctDNA

At Goffin, we are proud to be the exclusive supplier of nucleosomal ctDNA (n-ctDNA), a top-tier reference material recognized for its industry-leading low mutation background noise. This product ensures superior sensitivity and precision, making it ideal for achieving the lowest Limits of Blank (LOB), Detection (LOD), and Quantification (LOQ) in Next Generation Sequencing (NGS) assays, including highly specialized Minimal Residual Disease (MRD) tests.

Our n-ctDNA is produced from SensID’s proprietary lymphoblastoid cell line (BDXXP4), offering intensively characterized cfDNA with an exceptionally low error rate and excellent library conversion efficiency. Thanks to its patient-like fragmentation pattern, this reference material is perfectly suited for liquid biopsy research, diagnostic applications, and clinical trials in your laboratory or R&D department.

Additionally, Goffin can facilitate custom production from other cell lines upon request, ensuring flexibility and adaptability to meet specific research needs.

Components of the Nucleosome ctDNA
  • Nucleosome ctDNA (human, BDXXP4)

 

We recommend the use of our human DNA-free plasma products to produce complete workflow controls with this product. Blend the cfDNA as necessary with the DNA depleted plasma to receive plasma materials with the necessary DNA concentrations.

 

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