β-Globin StripAssay, tap a thumbnail to see more views.
β-Globin StripAssay
The β-globin strip assay from Viennalab is a molecular diagnostic test that detects genetic variants associated with hemoglobinopathies like sickle cell anemia and beta-thalassemia. The test is highly sensitive and specific, and can detect up to 10 different mutations in a single reaction, making it a reliable tool for identifying patients with hemoglobinopathies. The assay is easy to use and can be performed on a variety of sample types, including whole blood, dried blood spots, and buccal swabs. It is a valuable tool for genetic counseling, carrier screening, and prenatal diagnosis, and can be used for both research and clinical applications.
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This kit in detail
The β-globin strip assay from Viennalab is a molecular diagnostic test that detects genetic variants associated with hemoglobinopathies like sickle cell anemia and beta-thalassemia. The test is highly sensitive and specific, and can detect up to 10 different mutations in a single reaction, making it a reliable tool for identifying patients with hemoglobinopathies.
The assay is easy to use and can be performed on a variety of sample types, including whole blood, dried blood spots, and buccal swabs. It is a valuable tool for genetic counseling, carrier screening, and prenatal diagnosis, and can be used for both research and clinical applications.
- High sensitivity and specificity
- Comprehensive detection of up to 10 mutations in a single reaction
- Easy-to-use design
- Versatility with sample types
- Usefulness for both research and clinical applications
The beta (β)-globin strip assay from Viennalab is a molecular diagnostic test designed to detect genetic variants associated with hemoglobinopathies such as sickle cell anemia and beta-thalassemia. This assay is a fast and reliable tool for identifying patients who may carry these mutations, allowing for earlier diagnosis and appropriate treatment.
The β-globin strip assay utilizes a reverse hybridization method, in which PCR amplification is followed by hybridization of the biotin-labeled PCR product to specific probes immobilized on a nitrocellulose membrane strip. This allows for the detection of various beta-globin gene mutations through the appearance of specific hybridization signals on the strip.
The β-globin strip assay is a qualitative test that can detect various beta-globin gene mutations, including the most common mutations associated with sickle cell anemia and beta-thalassemia. The test is designed to detect up to 10 different mutations in a single reaction, providing a comprehensive diagnostic tool for patients with hemoglobinopathies.
One of the key advantages of the β-globin strip assay is its high sensitivity and specificity. The assay has been shown to have a sensitivity of 99% and a specificity of 100%, making it a highly reliable tool for identifying patients with hemoglobinopathies. Additionally, the assay is easy to use and does not require specialized equipment, making it accessible for laboratories with limited resources.
The β-globin strip assay can be used for both research and clinical applications, providing a valuable tool for genetic counseling, carrier screening, and prenatal diagnosis. The test can be performed on a variety of sample types, including whole blood, dried blood spots, and buccal swabs, making it a flexible and versatile tool for genetic testing.
In summary, the β-globin strip assay from Viennalab is a fast, reliable, and easy-to-use molecular diagnostic tool for identifying genetic variants associated with hemoglobinopathies. The assay’s high sensitivity and specificity, along with its ability to detect multiple mutations in a single reaction, make it a valuable tool for both research and clinical applications.
- DNA extraction reagents
- PCR amplification mix
- Biotin-labeled PCR product
- Nitrocellulose membrane strip with immobilized probes
- Streptavidin-alkaline phosphatase conjugate
- Detection reagents
- Positive and negative controls
- Instruction manual
Datasheets and regulatory documentation
Everything your quality team needs for evaluation and procurement.
Instructions for Use
Frequently paired with this kit
Other assays and instruments lab teams add alongside the β-Globin StripAssay.
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