fastGEN BCR::ABL1 Cancer Kit
The BCR::ABL1 fusion gene is the most important genetic marker for chronic myeloid leukemia. Patients with Philadelphia chromosome-positive leukemia may benefit from three generations of tyrosine kinase inhibitors.
Quote-based, no public pricing. Add to your quote and our specialists put together a proposal with the right documentation, typically within 24 hours.
This kit in detail
Description
Compatible with all Illumina platforms, for other platforms use conversion kit.
Summary
Hyperactivation of the oncogenic tyrosine kinase ABL1 leads to cell cycle aberrations. Increased genomic instability coupled with reduced repair capacity leads to accumulation of secondary mutations, conformational changes, ineffectiveness of some tyrosine kinase inhibitors and treatment failure.
There is a need to diagnose the mutational status of these variants and their response to current treatment options and possibly develop new targeted molecular therapies. The fastGEN BCR::ABL1 Cancer Kit from BioVendor Group is the first commercial NGS-based solution capable of covering the most common breakpoint cluster regions.
Together with our fastGEN Cancer Kits for TP53 and isocitrate dehydrogenase; BCR::ABL1 Cancer Kit will be a useful tool to improve treatment options for hemato-oncology patients worldwide.
Bioinformatic analysis software: GENOVESA
The GENOVESA fastGEN software module, available online, can be used to analyse sequencing data. It is an all-in-one cloud solution for raw data analysis (FASTQ files), with technical and application support.
Specifications
- Product: fastGEN BCR::ABL1 Cancer Kit
- Cat. No. — fastGEN BCR::ABL1 Cancer Kit: RDNGS0011 — 16 samples (1 kit)
- Cat. No. — fastGEN BCR::ABL1 Extra Sequencing Primers: RDNSP0011A
- Regulatory status: RUO
- Type: fastGEN
- Species: Human
- Research topic: Oncology
- Reconstitution: No
- Applications: Isolated DNA
fastGEN BCR::ABL1 Extra Sequencing Primers
Description
Do you need extra sequencing primers suitable for the fastGEN BCR::ABL1 Cancer Kit?
- Shipping: At -20°C temperature. Upon receipt, store the product at the temperature -20°C.
- Storage/Expiration: Store the complete kit at -20°C. Under these conditions, all components are stable until the expiration date (see label on the box).
Datasheets and regulatory documentation
Everything your quality team needs for evaluation and procurement.
Example Instructions for Use (RUO)
Safety Information (RUO)
Supporting Documents — Run Assignment
Supporting Documents — Application documents
Product Brochure
Safety Information (RUO)
Supporting Documents — Run Assignment
Supporting Documents — Application documents
Frequently paired with this kit
Other assays and instruments lab teams add alongside the fastGEN BCR::ABL1 Cancer Kit.
Add this kit to your quote
Tell us the platforms and throughput you’re planning for and our specialists will put together a clear proposal with the right documentation, no public pricing, just a considered answer.
