NPM1 Mutation Kit
The NPM1™ Mutation Detection Kit is a streamlined, single-assay solution designed for the rapid identification of critical NPM1 mutations in Acute Myeloid Leukemia (AML). Engineered with an integrated dual-purpose positive control, the kit ensures reliable analytical performance and consistency across assays. Ideal for research use, the kit supports workflows aiming for fast, accurate detection of NPM1 mutations, providing confidence in experimental AML studies. Note that this kit is for Research Use Only (RUO).
Quote-based, no public pricing. Add to your quote and our specialists put together a proposal with the right documentation, typically within 24 hours.
This kit in detail
- One-Step Multiplex Detection
- Integrated Positive Control
- High Sensitivity & Specificity
- Seamless Integration
NPM1 Mutation Kit: Your Ultimate Research Companion for AML
The NPM1™ Mutation Detection Kit transforms how researchers study Acute Myeloid Leukemia (AML) by providing a comprehensive, reliable, and efficient solution for detecting key NPM1 gene mutations. Focused on mutations A, B, and D, this kit condenses multiple testing steps into a single real-time PCR assay, reducing hands-on time and laboratory complexity while maintaining exceptional analytical precision.
At the heart of this kit is an integrated dual-purpose positive control, designed to ensure consistent PCR functionality and provide guidance for qualitative interpretation. This unique feature gives research teams confidence in the reliability of their results, mitigating the risks of false negatives or inconsistent data. By combining functionality verification and interpretative support, the positive control reinforces both workflow efficiency and experimental reproducibility.
Designed for Accuracy and Reliability
Precision is central to the NPM1™ Mutation Detection Kit. Each component is developed to the highest standards, guaranteeing consistent and reproducible results in every assay. The kit’s design emphasizes high sensitivity and specificity, making it an indispensable resource for molecular biology research focused on AML. Researchers can trust the kit to detect NPM1 mutations with minimal variability, supporting robust data generation and reliable experimental outcomes.
Innovations in Efficiency
By enabling one-step amplification of multiple NPM1 mutations, the kit optimizes laboratory workflows, allowing teams to obtain comprehensive mutation profiles faster and with fewer resources. This efficiency translates into both time and cost savings, enabling laboratories to focus on research insights rather than repetitive procedural steps.
Additionally, the kit is engineered for seamless integration into broader AML research workflows. Whether paired with genomic extraction kits, sequencing platforms, or complementary molecular assays, the NPM1™ Mutation Detection Kit provides a cohesive solution for advanced AML research projects.
Supporting Research Excellence
The kit has undergone thorough validation using reference materials from certified synthetic vectors and established biobanks. This rigorous testing ensures the method is robust, reproducible, and specific, supporting reliable AML research outcomes. For laboratories aiming to maintain high standards of data quality, the NPM1™ Mutation Detection Kit represents a research-grade solution that balances performance, reliability, and workflow efficiency.
Conclusion
The NPM1™ Mutation Detection Kit is s a research companion for laboratories committed to advancing AML molecular biology studies. Its combination of high accuracy, streamlined multiplex detection, integrated positive control, and robust validation supports reproducible and efficient workflows. By choosing this kit, research teams are investing in a system designed to enhance experimental precision, reduce procedural complexity, and contribute to meaningful scientific insights.
Whether for large-scale studies or focused mutation analyses, the NPM1™ Mutation Detection Kit delivers the quality, reliability, and operational simplicity needed in modern molecular research. It epitomizes the evolution of AML research tools, helping laboratories translate complex molecular insights into actionable scientific knowledge.
The kit contents the necessary reagents to perform 24 reactions. The reagents included in the kit are the following:
- NPM1 Master Mix: Specific oligonucleotides, labelled probes and water reagents for the PCR
reactions. - General Master Mix: Conventional PCR enzyme containing 10-30% glycerine.
- NPM1 Control: Positive control containing the sequence of the NPM1 A type mutation.
Datasheets and regulatory documentation
Everything your quality team needs for evaluation and procurement.
Instructions for Use
MSDS NPM1 Mutation Kit
Frequently paired with this kit
Other assays and instruments lab teams add alongside the NPM1 Mutation Kit.
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