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Pharmacogenetics
Agena Distributed by Goffin Diagnostics

VeriDose CYP2D6 CNV panel

The Agena VeriDose CYP2D6 CNV Panel determines the copy number of the CYP2D6 gene on the MassARRAY platform, with iPLEX Pro chemistry. Research use only. Copy number is what a variant panel cannot see: deletions and duplications of the whole gene change the metaboliser status regardless of which star alleles are present. The software reports diplotype, haplotype and copy number in one call.

RUO Agena 1 Set (10x384 samples), 1 Set (10x96 samples), 1 Set (2x384 samples), 1 Set (2x96 samples)
Brand
Agena
Packaging
1 Set (10x384 samples), 1 Set (10x96 samples), 1 Set (2x384 samples), 1 Set (2x96 samples)
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Quote-based, no public pricing. Add to your quote and our specialists put together a proposal with the right documentation, typically within 24 hours.

Product details

This kit in detail

  • Copy number analysis of CYP2D6
  • Software reports diplotype, haplotype and CNV
  • iPLEX Pro chemistry on the MassARRAY platform
  • 96-well and 384-well formats, hundreds to thousands of samples a day
  • Results within a single day
  • Catalogue 13372F, 13360F, 13362D and 13361D, with control 02005

The Agena VeriDose CYP2D6 CNV Panel determines the number of copies of the CYP2D6 gene, the step that completes a CYP2D6 genotype. Research use only.

Why copy number matters

CYP2D6 metabolises a large share of clinically used drugs, including tamoxifen, opioids, antidepressants and antipsychotics. A variant panel reports which star alleles are present, but a whole-gene deletion or duplication changes the enzyme activity independently of those alleles: a duplicated functional allele produces an ultrarapid metaboliser, a deletion an intermediate or poor one. Without copy number the phenotype prediction stays incomplete.

Format

The panel runs with iPLEX Pro chemistry on the MassARRAY platform, in a 96-well and a 384-well format, and scales to hundreds or thousands of samples a day with results in a single day. Automated software provides the diplotype, the haplotype and the copy number call. Catalogue numbers are 13372F and 13360F for the 96 format, 13362D and 13361D for the 384 format, with control 02005.

Regulatory status

This product is for research use only and not for use in diagnostic procedures.

  • PCR Reagents
  • Detection probes
  • Control Samples
  • Buffers and Solutions
  • Instructions for use
Documentation

Datasheets and regulatory documentation

Everything your quality team needs for evaluation and procurement.

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