Genetic Disorders · Catalog
α-Globin
About α-Globin
The α-globin genes, HBA1 and HBA2, located on chromosome 16, control the production of the a-globin chain. They are a part of the alpha-globin gene family, which also includes two pseudogenes with similar sequences but do not encode functional proteins. A tightly controlled process balances the production of alpha and beta chains to ensure efficient hemoglobin function.
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