HLA-B27 StripAssay

Spondyloarthropathies and HLA-B27

Spondyloarthropathies, including conditions like ankylosing spondylitis and reactive arthritis, are often challenging to diagnose due to their vague and overlapping symptoms. These diseases primarily affect the joints and spine, causing chronic pain, stiffness, and inflammation. Early diagnosis is essential to prevent long-term damage and manage symptoms effectively. The HLA-B27 genetic marker is closely linked to these conditions, and detecting its presence can significantly aid in diagnosing these disorders.

The HLA-B27 StripAssay®: A Comprehensive Diagnostic Tool

The StripAssay® is designed to identify not only the HLA-B27 allele but also multiple variants associated with spondyloarthropathies. This approach makes it reliable in offering detailed genetic information. The test follows a straightforward three-step process: DNA isolation, PCR amplification, and hybridization to a test strip with specific probes. This simplicity, combined with a complete kit of necessary components, ensures ease of use, even in laboratories without advanced molecular biology expertise.

Accurate Results for Better Diagnosis

The StripAssay® employs advanced PCR and reverse-hybridization techniques, delivering highly accurate diagnostic results. The results are visualized through a clear enzymatic color reaction, which can be easily interpreted without specialized equipment. By integrating this test into diagnostic workflows, healthcare providers can make quicker and more accurate diagnoses of spondyloarthropathies, leading to more timely and effective treatment for patients.

• Lysis Solution (50 ml)
• GENXTRACT™ Resin (5 ml)
• Amplification Mix with yellow cap (500 µl)
• Taq Dilution Buffer with transparent cap (500 µl)
• DNAT with blue cap (1.5 ml)
• Typing Trays (3)
• Teststrips (20)
• Hybridization Buffer with white cap (25 ml)
• Wash Solution A with white cap (80 ml)
• Conjugate Solution (25 ml)
• Wash Solution B (80 ml)
• Color Developer (25 ml)
• Collector™ Sheet (1)