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The Viennalab CYP2D6 CNV PCR Kit detects common genetic variants and copy number changes in Caucasians associated with poor, intermediate, or ultrarapid CYP2D6 metabolizer status. The CYP2D6 gene is involved in the metabolism of approximately 25% of drugs used in the clinic, and genetic variations contribute to inter-individual variability in drug response.
By identifying patients with altered CYP2D6 enzyme function, informed drug prescribing recommendations and drug dosage adjustments can be made, reducing the risk of adverse events or lowered treatment efficacy. Clinical guidelines are listed on PharmGKB, and approximately 6% of Europeans are poor metabolizers, 7% are intermediate metabolizers, and 3% are ultrarapid metabolizers. The Viennalab CYP2D6 PCR Kit facilitates personalized medicine and ensures patient safety.
CYP2D6 genetic variations are associated with inter-individual variability in drug response, making it crucial to identify patients with altered CYP2D6 enzyme function. The Viennalab CYP2D6 PCR Kit covers the most clinically relevant loss-of-function, reduced function, and increased function alleles, including *3 – *8, *11, *12, *15, *40, *58, *9, *10, *14, *17, *29, *41, *1xN, *2xN, and *35xN (N=copy number). By referring to the clinical guidelines listed on PharmGKB, you can make informed drug prescribing recommendations and reduce the risk of adverse events or lowered treatment efficacy.
Approximately 6% of Europeans are poor metabolizers, 7% are intermediate metabolizers, and 3% are ultrarapid metabolizers. The PGX-CYP2D6 XL StripAssay® in combination with the CYP2D6 RealFastTM CNV Assay enables you to identify patients with altered CYP2D6 enzyme function, facilitating the choice of medication and/or adjustment of drug dosage. This, in turn, reduces the risk of adverse events or lowered treatment efficacy, ensuring the safety and well-being of your patients.
Don’t let CYP2D6 genetic variations compromise your patients’ drug response – invest in the Viennalab CYP2D6 PCR Kit today and take your personalized medicine approach to the next level!
The kit also includes instructions for use, as well as a protocol for the detection of CNVs in the CYP2D6 gene using real-time PCR.
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