VeriDose DPYD panel
The Agena VeriDose DPYD Panel genotypes 9 single nucleotide variants in the DPYD gene in a single well on the MassARRAY platform. The variants concern the risk of toxicity from fluoropyrimidines: 5-fluorouracil, capecitabine and tegafur. Research use only. The panel is supplied in a 96 and a 384 format, covering 960 and 3,840 samples per set.
Quote-based, no public pricing. Add to your quote and our specialists put together a proposal with the right documentation, typically within 24 hours.
This kit in detail
- 9 DPYD single nucleotide variants in one well
- Concerns toxicity risk from 5-fluorouracil, capecitabine and tegafur
- Runs on the MassARRAY platform
- 96 format: 960 samples per set, catalogue 13330F
- 384 format: 3,840 samples per set, catalogue 13331D
The Agena VeriDose DPYD Panel determines the DPYD genotype before treatment with a fluoropyrimidine, on the MassARRAY platform. Research use only.
Clinical background
Dihydropyrimidine dehydrogenase clears fluoropyrimidines. Variants that reduce that activity let the drug accumulate, and carriers develop severe toxicity at a standard dose. 5-fluorouracil, capecitabine and tegafur are widely used in solid tumours, which is why genotyping before the first dose has become standard practice in several countries.
Format
The panel multiplexes 9 variants in a single well. The 96 format (catalogue 13330F) covers 960 samples per set of ten plates, the 384 format (catalogue 13331D) covers 3,840. Because the panel runs on the MassARRAY platform, it can be combined with the other VeriDose panels in the same laboratory workflow.
Regulatory status
This product is for research use only and not for use in diagnostic procedures.
- PCR Reagents
- Positive and Negative Control Samples
- Buffers and Solutions
- Array/Chip
- Instructions for use
Datasheets and regulatory documentation
Everything your quality team needs for evaluation and procurement.
Frequently paired with this kit
Other assays and instruments lab teams add alongside the VeriDose DPYD panel.
Add this kit to your quote
Tell us the platforms and throughput you’re planning for and our specialists will put together a clear proposal with the right documentation, no public pricing, just a considered answer.
