Huntington Disease Kit
The Imegen® Huntington Disease Kit offers semi-quantitative analysis of CAG expansion repetitions within the HTT gene through two PCR assays (HTT-C and HTT-L). It covers an amplification range of 100-500 base pairs and includes a positive control with normal alleles for all kit assays. Note that this kit is for Research Use Only (RUO).
Quote-based, no public pricing. Add to your quote and our specialists put together a proposal with the right documentation, typically within 24 hours.
This kit in detail
The Imegen® Huntington Disease Kit offers semi-quantitative analysis of CAG expansion repetitions within the HTT gene through two PCR assays (HTT-C and HTT-L). It covers an amplification range of 100-500 base pairs and includes a positive control with normal alleles for all kit assays.
Note that this kit is for Research Use Only (RUO).
- CAG Expansion Analysis
- Semi-quantitative PCR
- Positive Control Included
- Compatible Thermal Cyclers
Product Overview: Imegen® Huntington Disease Kit enables semi-quantitative analysis of CAG expansion in the HTT gene through HTT-C and HTT-L PCR assays, covering a 100-500 bp amplification range. It includes a positive control with normal alleles.
Key Features:
- Semi-Quantitative CAG Analysis
- Dual PCR Assays (HTT-C and HTT-L)
- Amplification Range: 100-500 bp
- Included Positive Control
- Compatible with Neurodegenerative Disease Assays
- DNA Requirement: 50 ng per Reaction
- Sample Type: Peripheral Blood
- 2 Reactions per Sample
- Targets: CAG and poly-CCG
- Quick Setup (45 mins)
- PCR Program Duration: 2h 15 mins
- Compatible with Standard Cyclers
- Sequencing with 6-Carboxyfluorescein (6-FAM) and NEDTM
About Huntington’s Disease: Huntington’s Disease is an inherited neurodegenerative disorder causing progressive brain neuron degeneration, impacting motor skills, cognition, and mental health. Diagnosis hinges on CAG triplet repeat analysis, with <26 repeats as normal, 27-35 intermediate, and >36 as pathological.
Imegen® Huntington Kit offers precise CAG expansion analysis with HTT-C (short-range) and HTT-L (long-range) PCR, covering polymorphic poly-CCG fragments. Sequencing via 6-FAM and NEDTM-labeled PCR products separates amplicons for size analysis.
Huntington Master Mix, General Master Mix IV, HTT-L Master Mix, HTT-C Master Mix and Positive Control
Datasheets and regulatory documentation
Everything your quality team needs for evaluation and procurement.
Instructions for Use
Imegen® Huntington Disease Kit
Frequently paired with this kit
Other assays and instruments lab teams add alongside the Huntington Disease Kit.
Add this kit to your quote
Tell us the platforms and throughput you’re planning for and our specialists will put together a clear proposal with the right documentation, no public pricing, just a considered answer.
