KleeYa® Automated CLIA Analyser

CLIA method

Chemiluminescence immunoassay (CLIA) combines chemiluminescent technology with immunochemical reactions. CLIA technology involves the immobilization of an acridinium ester-labelled antigen-antibody complex on a solid base. Acridinium ester molecules have the dominant property of not losing luminescent activity even after binding to an antigen or antibody. Acridinium ester exposed to an alkaline solution together with hydrogen peroxide causes a flash of light. The onset of light emission usually occurs within a few seconds. The reaction results in generation of light, the intensity of which is directly proportional to the amount of labelled complexes present and allows the quantification of the analyte.

Platform

German technology together with accurate Swiss production for modern, fast and reliable diagnostics

KleeYa ® pipettes for you. A reagent transfer pipettor with steel needle, and a special cartridge with assay reagents and disposable tips, make pipetting an elegant and contactless process minimising any risk of contamination.

The disposable reagent cartridge package is designed for continuous reagent consumption in vials, which by their design increase the reagent stability on board. Special Dynamic Sealing Caps prevent contamination and reduce the number of stell needle probe wash cycles. RFID tags make the tests maximally flexible and traceable. Reagents are supplied in working dilution – to save your time and ensure the maximum reliability of each test.

An advanced camera based barcode reader and two RFID tag readers provide the basis of an advanced platform for work and management of samples, reagents, and consumables. KleeYa ® technology works accurately and thanks to software connectivity to laboratory information system helps eliminate human errors. Because even the best laboratory technician is still just a human being.

Technical specifications

• Operating mode: Fully automated, continuous random access processing
• Design: Floorstanding
• Dimensions (Width x Depth x Height): 133 cm x 70 cm x 147 cm without touch screen
• Weight (kg): 277
• Input power: 100-240 VAC, 50-60 Hz
• Computer operating system: Microsoft Windows 10
• User interface: LCD touch monitor (integrated)
• Detection principle: Binding of the immunocomplex to magnetic particles with subsequent detection of chemiluminescence (flash)

Function

• Sample integrity check: Yes
• STAT functionality: Yes
• Reagent integrity check: Yes
• Washing station: Integrated
• Integrated code readers: Camera/RFID reader
• Maintenance: Daily/weekly/monthly
• LIS connection: Bidirectional

Analysis

• Max. throughput/hour: 120
• Number of different cartridges on board (capacity of reagent cartridges): 16
• Reaction carousel: Temperature 37°C ± 1°C
• Sample type: Biological fluids (serum, plasma, urine, whole blood, cerebrospinal fluid, aqueous solutions)
• Sample tubes: All up to 16 x 100 mm
• Capacity of samples on board: 72

Reagents

• Minimum pipetting volume of reagents: ≥10 μl
• Method of pipetting reagents: Pipetting arm
• Number of cuvettes stored on board: 500
• Processing volume of cuvettes: 600 μl
• Tip box – capacity: 192