ESR1 Reference Set cfDNA

Specifically designed as quality control material for lab developed tests (LDTs) and CE-IVD labelled assays.
ESR1 reference set serves as a quality control material for ESR1 mutation assays on cell free DNA (cfDNA) level. The selection of mutations was reviewed and endorsed by various experts in the field and ESR1 test developers.
In several retrospective cohorts, estrogen receptor 1 (ESR1) mutations have been reported in approximately 11%–55% of estrogen receptor (ER) positive + metastatic breast cancer patients treated with aromatase inhibitors (AIs) (1).