The iPLEX® Pro Sample ID Panel uses advanced genetic technology to accurately identify and authenticate samples in genetic testing. By analyzing 44 SNPs to create a genetic fingerprint for each sample, it efficiently detects any mismatches. This panel is particularly crucial in addressing common lab challenges like sample mix-ups and quality control, ensuring the integrity of results. With its ability to work with as little as 10 ng of cfDNA and deliver results in just 8 hours, it streamlines the testing process. The panel also includes an automated reporter for easy interpretation of match or mismatch results, making it a essential tool for labs seeking to improve accuracy and reduce errors in sample identification.
iPLEX® Pro Sample ID Panel: Streamlining Sample Verification in Genetic Testing
In genetic testing, it’s really important to correctly identify and check the quality of samples. The iPLEX® Pro Sample ID Panel meets this need by providing a reliable way to accurately identify and authenticate samples.
Improving Sample Identification with Genetic Fingerprints
The iPLEX® Pro Sample ID Panel utilizes 44 SNPs (Single Nucleotide Polymorphisms) to create a unique genetic fingerprint for each sample. This fingerprint is analyzed using the MassARRAY® system, a reliable and precise platform. The automated reporter software then compares the SNP profiles and generates a “Match” or “Mismatch” result, providing a clear, easy-to-understand indication of sample authenticity. This level of accuracy is crucial, especially considering the estimation that 1 in every 200 samples in laboratories might be mixed up.
Addressing the Issue of Sample Mix-Ups
Sample mix-ups, often occurring outside the lab, can lead to incorrect results and damage the reputation of a lab. Traditional quality checks fall short in detecting such errors. The iPLEX® Pro Sample ID Panel effectively tackles this challenge, enhancing the integrity of laboratory testing and results.
Improving Downstream Analysis Success Rate
A significant percentage of samples, about 22.5%, fail in downstream molecular analysis due to low quantity or poor-quality DNA. Traditional DNA quality measurements, often based on absorbance, may not accurately reflect the amount of amplifiable DNA, leading to wasted time and resources. The iPLEX® Pro Sample ID Panel not only identifies samples but also measures DNA quality. It uses SNPs and biological gender markers for creating a genetic fingerprint, and amplification is compared to built-in controls to determine the quantity of amplifiable DNA present.
On-Demand Panels for Rapid Testing
These pre-designed panels are available for on-demand ordering, facilitating quick setup and testing. They use the proven iPLEX Pro chemistry and can be processed alongside other applications in the same run, making them a versatile addition to any laboratory.
The iPLEX Pro Sample Integrity panels come with reporting software that simplifies sample identity and DNA quality determination. The automated reports provide essential information like biological gender, the number of amplifiable DNA copies, and match/mismatch analysis.
Summary Report for Quality Control
The summary report offers a quick overview, highlighting potential sample mismatches or issues with quality control. It includes:
Conclusion
The iPLEX® Pro Sample ID Panel is a tool for genetic testing laboratories, ensuring the accuracy and integrity of sample identification and DNA quality assessment. Its comprehensive approach, coupled with rapid and user-friendly analysis, significantly enhances the reliability of genetic testing, contributing to better research outcomes and patient care.
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