The Chimerism Multiplex II Kit offers an advanced method for tracking transplant progression, allowing targeted treatments to preempt risks like relapse or graft-versus-host disease. It employs real-time PCR to simultaneously analyze 34 markers across 18 chromosomes, ensuring high specificity and broad applicability. With the inclusion of SRY and RhD markers, the kit’s cumulative informativity reaches 99.4%.
A powerful tool for professionals in molecular biology, this kit raises the bar in hematopoietic stem cell transplant monitoring.
Instructions for Use
MSDS Chimerism Multiplex II Kit
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Chimerism Multiplex II Kit: Pioneering Advanced Chimerism Analysis
In the intricate landscape of molecular biology, one area that holds significant clinical promise is the analysis of molecular chimerism. The Chimerism Multiplex II Kit provides a robust toolset for researchers and clinicians aiming to shed light on the intricacies of allogenic transplantation and its long-term implications, such as graft-versus-host disease, rejection, or relapse.
Central to the Chimerism Multiplex II Kit is its multiplexed real-time PCR diagnostic assay. Designed with a precise blend of oligonucleotides and fluorescent hydrolysis probes, this kit provides simultaneous analysis of 16 insertion/deletion polymorphisms (INDELs) in 8 independent PCR reactions. What sets it apart is its ability to isolate informative markers found in the transplant recipient but absent in the donor, delivering unparalleled accuracy and insight.
The art of this kit lies in its multiplexing capabilities. In a single procedural step, it identifies the presence or absence of 16 polymorphic markers. Each marker is uniquely tagged with a specific fluorophore, rendering results that are not just accurate but also unambiguous. Notably, the kit includes gender-specific SRY markers and RhD blood type markers as built-in elements, obviating the need for additional tests to establish informativity.
Features Crafted for Research Excellence
Embracing the Future of Chimerism Analysis
The Chimerism Multiplex II Kit represents a paradigm shift in the domain of molecular chimerism analysis. It invites professionals to explore a new era of targeted, personalized treatment modalities post-allogenic transplantation. For those who are at the frontier of molecular biology and patient care, this is your toolkit for innovation. The future of chimerism analysis is not just approaching; it’s already here.
The kit contians the necessary reagents to perform 10 reactions. The reagents included in the kit are the following:
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